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Sirtuin 1 in Host Defense during Infection

19 Sept 2022

Abstract excerpt

Sirtuins (SIRTs) are members of the class III histone deacetylase family and epigenetically control multiple target genes to modulate diverse biological responses in cells. Among the SIRTs, SIRT1 is the most well-studied, with a role in the modulation of immune and inflammatory responses following infection. The functions of SIRT1 include orchestrating immune, inflammatory, metabolic, and autophagic responses,...

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PMID: 36139497
DOI: 10.3390/cells11182921

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