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The Versatility of Sirtuin-1 in Endocrinology and Immunology

19 Nov 2020

Abstract excerpt

Sirtuins belong to the class III family of NAD-dependent histone deacetylases (HDAC) and are involved in diverse physiological processes that range from regulation of metabolism and endocrine function to coordination of immunity and cellular responses to stress. Sirtuin-1 (SIRT1) is the most well-studied family member and has been shown to be critically involved in epigenetics, immunology, and endocrinology. The...

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PMID: 33330467
DOI: 10.3389/fcell.2020.589016

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