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Article

SIRT1: A Potential Therapeutic Target in Autoimmune Diseases

23 Nov 2021

Abstract excerpt

The morbidity and mortality of autoimmune diseases (Ads) have been increasing worldwide, and the identification of novel therapeutic strategies for prevention and treatment is urgently needed. Sirtuin 1 (SIRT1), a member of the class III family of nicotinamide adenine dinucleotide (NAD + )-dependent histone deacetylases, has been reported to participate in the progression of several diseases. SIRT1 also regulates...

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PMID: 34887866
DOI: 10.3389/fimmu.2021.779177

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