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The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic Pathways and Viral Infections

21 Feb 2021

Abstract excerpt

Sirtuins (SIRTs) are nicotinamide adenine dinucleotide-dependent histone deacetylases that incorporate complex functions in the mechanisms of cell physiology. Mammals have seven distinct members of the SIRT family (SIRT1-7), which play an important role in a well-maintained network of metabolic pathways that control and adapt the cell to the environment, energy availability and cellular stress. Until recently,...

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PMID: 33669990
DOI: 10.3390/cells10020460

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