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Article

Causal effects of modifiable risk factors on obstructive sleep apnea: A Mendelian randomization study and validation study.

Medicine - 16 Jan 2026

Li Zhen

Abstract excerpt

Obstructive sleep apnea (OSA) is a chronic condition characterized by recurrent upper airway obstruction during sleep. The pathogenesis of OSA remains unclear, and few studies have systematically investigated causal associations with modifiable risk factors at the genetic level. This study used Mendelian randomization (MR) based on genome-wide association study (GWAS) data to evaluate potential causal effects of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41559995
DOI: 10.1097/MD.0000000000046771
PMCID: PMC12826191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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