Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell type-specific potential pathogenic genes and functional pathways in Alzheimer’s Disease

2 Oct 2021

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a pervasive age-related and highly heritable neurodegenerative disorder but has no effective therapy. The complex cellular microenvironment in the AD brain impedes our understanding of pathogenesis. Thus, a comprehensive investigation of cell type-specific responses in AD is crucial to provide precise molecular and cellular targets for therapeutic development. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neurogenesis and neuroplasticity mechanisms
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34600516
DOI: 10.1186/s12883-021-02407-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell type-specific potential pathogenic genes and functional pathways in Alzheimer’s DiseasePMID 34600516Read ↗

Accelerated aging-related transcriptome alterations in neurovascular unit cells in the brain of Alzheimer’s diseaseSemantic proximity Read ↗

Decoding cell-type-specific alterations in Alzheimer’s disease through scRNA-seq and network analysisSemantic proximity Read ↗

Single-Cell Cortical Transcriptomics Reveals Common and Distinct Changes in Cell-Cell Communication in Alzheimer’s and Parkinson’s DiseaseSemantic proximity Read ↗

Molecular and cellular pathology of monogenic Alzheimer’s disease at single cell resolutionSemantic proximity Read ↗

Altered immune response is associated with sex difference in vulnerability to Alzheimer's disease in human prefrontal cortexSemantic proximity Read ↗

The Alzheimer's Cell Atlas (TACA): A single‐cell molecular map for translational therapeutics accelerator in Alzheimer's diseaseSemantic proximity Read ↗

A single cell brain atlas in human Alzheimer’s diseaseSemantic proximity Read ↗

Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer’s DiseaseSemantic proximity Read ↗

Identification of molecular signatures associated with sleep disorder and Alzheimer’s diseaseSemantic proximity Read ↗

Identification of dysregulated genes and pathways of different brain regions in Alzheimer’s diseaseSemantic proximity Read ↗

Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathwaysSemantic proximity Read ↗

Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.