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Article

TNFAIP3 mutation is an independent poor overall survival factor for patients with T-cell acute lymphoblastic leukemia.

Cancer medicine - 1 Feb 2023

Chen Cunte, Zhou Lingling, Zhu Lihua, Luo Gengxin, Wang Liang, Zeng Chengwu, Zhou Hongsheng, Li Yangqiu

Abstract excerpt

BACKGROUND: It is imperative to explore potential biomarkers for predicting clinical outcome and developing targeted therapies for T-cell acute lymphoblastic leukemia (T-ALL). This study aimed to investigate the mutation patterns of tumor necrosis factor-alpha-inducing protein 3 (TNFAIP3, also known as A20) and its role in the prognosis of T-ALL patients. METHODS: Polymerase chain reaction (PCR) and Sanger...

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Share to Mutation
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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Share to Tumor Necrosis Factor alpha-Induced Protein 3

Source

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Identifiers

PMID: 36056685
DOI: 10.1002/cam4.5196
PMCID: PMC9972139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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