Article
Association of TNF-α rs1800629 with Adult Acute B-Cell Lymphoblastic Leukemia.
Genes - 13 Jul 2022
Abdalhabib Ezeldine K, Algarni Abdulrahman, Saboor Muhammad, Alanazi Fehaid, Ibrahim Ibrahim K, Alfeel Ayman H, Alanazi Abdullah M, Alanazi Abdulmajeed M, Alruwaili Abdulaziz M, Alanazi Muath H, Alshaikh Nahla A
Abstract excerpt
TNF−α influences lymphomagenesis by upregulating proinflammatory and antiapoptotic pathways. In this study, we evaluated the frequency of TNF−α rs1800629 (−308 G>A) polymorphism in newly diagnosed adult patients with acute lymphoblastic leukemia (ALL) and its correlation with age at diagnosis, gender and subtype of ALL. In this case control study, a total of 330 individuals were recruited, including 165 newly...
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