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Article

Deciphering autoimmune susceptibility: a meta-analysis of PTPN22 gene variants.

Immunologic research - 11 Mar 2025

Thomas Sheena Mariam, Veerabathiran Ramakrishnan

Abstract excerpt

Autoimmune disorders are intricate conditions where the immune system directs its attack towards the body's tissues. The goal is to perform a thorough meta-analysis focusing on the genetic and epigenetic aspects of autoimmune disorders, specifically examining the role of the PTPN22 gene, particularly the rs2476601 variation, in influencing susceptibility to autoimmune diseases. The study followed PRISMA 2020...

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Source

Identifiers

PMID: 40067478
DOI: 10.1007/s12026-025-09614-9

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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