Article
Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.
Gastroenterology - 1 May 2017
Matsuura Kentaro, Sawai Hiromi, Ikeo Kazuho, Ogawa Shintaro, Iio Etsuko, Isogawa Masanori, Shimada Noritomo, Komori Atsumasa, Toyoda Hidenori, Kumada Takashi, Namisaki Tadashi, Yoshiji Hitoshi, Sakamoto Naoya, Nakagawa Mina, Asahina Yasuhiro, Kurosaki Masayuki, Izumi Namiki, Enomoto Nobuyuki, Kusakabe Atsunori, Kajiwara Eiji, Itoh Yoshito, Ide Tatsuya, Tamori Akihiro, Matsubara Misako, Kawada Norifumi, Shirabe Ken, Tomita Eiichi, Honda Masao, Kaneko Shuichi, Nishina Sohji, Suetsugu Atsushi, Hiasa Yoichi, Watanabe Hisayoshi, Genda Takuya, Sakaida Isao, Nishiguchi Shuhei, Takaguchi Koichi, Tanaka Eiji, Sugihara Junichi, Shimada Mitsuo, Kondo Yasuteru, Kawai Yosuke, Kojima Kaname, Nagasaki Masao, Tokunaga Katsushi, Tanaka Yasuhito
Abstract excerpt
BACKGROUND & AIMS: There is still a risk for hepatocellular carcinoma (HCC) development after eradication of hepatitis C virus (HCV) infection with antiviral agents. We investigated genetic factors associated with the development of HCC in patients with a sustained virologic response (SVR) to treatment for chronic HCV infection. METHODS: We obtained genomic DNA from 457 patients in Japan with a SVR to...
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