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Article

The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility.

BMC cancer - 7 Feb 2012

Junjie Xie, Songyao Jiang, Minmin Shi, Yanyan Song, Baiyong Shen, Xiaxing Deng, Jiabin Jin, Xi Zhan, Hao Chen

Abstract excerpt

BACKGROUND: Toll-like receptors (TLR) are key innate immunity receptors participating in an immune response. Growing evidence suggests that mutations of TLR2/TLR9 gene are associated with the progress of cancers. The present study aimed to investigate the temporal relationship of single nucleotide polymorphisms (SNP) of TLR2/TLR9 and the risk of hepatocellular carcinoma (HCC). METHODS: In this single center-based...

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Source

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Identifiers

PMID: 22309608
DOI: 10.1186/1471-2407-12-57
PMCID: PMC3311588

Genes

TLR2
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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