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Article

Polymorphisms of toll-like receptors and their pathways in viral hepatitis.

Antiviral therapy - 1 Jan 2011

Sawhney Rohit, Visvanathan Kumar

Abstract excerpt

Toll-like receptors (TLRs) are an important part of the innate immune response to a variety of pathogens including hepatic viral infections. Activation of TLRs stimulates a complex intracellular signalling cascade that results in production of proinflammatory cytokines and interferons important for antiviral responses as well as induction of the adaptive arm of the immune system. There is substantial evidence for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21685532
DOI: 10.3851/IMP1820

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