Allogeneic Hematopoietic Stem Cell Transplantation with Myeloablative Conditioning Is Associated with Favorable Outcomes in Mixed Phenotype Acute Leukemia.

doi:10.1016/j.bbmt.2017.06.026

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Article

Allogeneic Hematopoietic Stem Cell Transplantation with Myeloablative Conditioning Is Associated with Favorable Outcomes in Mixed Phenotype Acute Leukemia.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Nov 2017

Getta Bartlomiej M, Roshal Mikhail, Zheng Junting, Park Jae H, Stein Eytan M, Levine Ross, Papadopoulos Esperanza B, Jakubowski Ann A, Kernan Nancy A, Steinherz Peter, O'Reilly Richard J, Perales Miguel-Angel, Giralt Sergio A, Tallman Martin S, Shaffer Brian C

Abstract excerpt

Mixed phenotype acute leukemia (MPAL) represents a poorly characterized group of acute leukemias that lack an accepted therapeutic approach and are typically associated with poor outcomes. We present our experience of genomic profiling, pretransplantation therapy, and transplantation outcomes for 36 well-characterized pediatric and adult patients with MPAL, defined according to the 2016 World Health Organization...

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Identifiers

PMID: 28694182
DOI: 10.1016/j.bbmt.2017.06.026
PMCID: PMC5682215

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