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Human coronaviruses disassemble processing bodies

23 Aug 2022

Abstract excerpt

A dysregulated proinflammatory cytokine response is characteristic of severe coronavirus infections caused by SARS-CoV-2, yet our understanding of the underlying mechanism responsible for this imbalanced immune response remains incomplete. Processing bodies (PBs) are cytoplasmic membraneless ribonucleoprotein granules that control innate immune responses by mediating the constitutive decay or suppression of mRNA...

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PMID: 35998203
DOI: 10.1371/journal.ppat.1010724

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