Article
Lack of association of the KIR and HLA class I ligands with ZIKV infection in south and southeast of Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Jan 2022
Elpidio Laise Nayana Sala, de Moraes Amarilis Giaretta, Langer Ieda Bernadete Volkweis, do Amaral Greicy Cezar, Moretti Maria Luiza, Garcia Márcia Teixeira, Angerami Rodrigo, Proenca-Modena José Luiz, Bispo-Dos-Santos Karina, Martini Matheus Cavalheiro, Parise Pierina Lorencini, Ayo Christiane Maria, de Mattos Luiz Carlos, Brandão Cinara Cássia, Nogueira Maurício Lacerda, Oliani Denise Cristina Mós Vaz, Spegiorin Lígia Cosentino Junqueira Franco, de Lima Neto Quirino Alves, Visentainer Jeane Eliete Laguila
Abstract excerpt
BACKGROUND: Zika virus (ZIKV) is an emerging arbovirus associated with foetal malformations and neurological complications. The infection is usually associated with mild symptoms. The comparison between the allelic frequency of polymorphic genes in symptomatic infected individuals in the population can clarify the pathogenic mechanisms of ZIKV. During ZIKV infection, cytokines are produced and natural killer (NK)...
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