Article
Can presence of HLA type I and II alleles be associated with clinical spectrum of CHIKV infection?
Transboundary and emerging diseases - 1 Jul 2022
Rueda Juan C, Santos Ana M, Angarita Jose-Ignacio, Saldarriaga Eugenia-Lucia, Peláez-Ballestas Ingris, Espinosa Alejandro Silva, Briceño-Balcázar Ignacio, Arias-Correal Sofia, Arias-Correal Jose, Villota-Erazo Catalina, Reyes Viviana, Bernal-Macías Santiago, Cardiel Mario H, Londono John
Abstract excerpt
Host immune response and virulence factors are key to disease susceptibility. However, there are no known association studies of human leukocyte antigen (HLA) class I and II alleles with chikungunya virus (CHIKV) infection in the Latin American population. Here, we aimed to identify HLA alleles present in patients with CHIKV infection versus healthy controls as well as the allelic association with the clinical...
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