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Article

Killer cell immunoglobulin-like receptor (KIR) gene diversity in a population naturally exposed to malaria in Porto Velho, Northern Brazil.

Tissue antigens - 1 Mar 2015

Perce-da-Silva D S, Silva L A, Lima-Junior J C, Cardoso-Oliveira J, Ribeiro-Alves M, Santos F, Porto L C M S, Oliveira-Ferreira J, Banic D M

Abstract excerpt

Killer cell immunoglobulin-like receptors (KIR) are expressed mainly in natural killer cells and specifically recognize human leukocyte antigen (HLA) class I molecules. The repertoire of KIR genes and KIR-HLA pairs is known to play a key role in the susceptibilities to and the outcomes of several diseases, including malaria. The aim of this study was to investigate the distribution of KIR genes, KIR genotypes and...

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PMID: 25656387
DOI: 10.1111/tan.12523

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