Article
Peripheral spectrum neurological disorder after arbovirus infection is associated with HLA-F variants among Northeastern Brazilians.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2021
Sonon Paulin, Collares Cristhianna V A, Ferreira Maria Lúcia Brito, Almeida Renata Santos, Sadissou Ibrahim, Cordeiro Marli Tenório, de Fátima Militão de Albuquerque Maria, Castelli Erick C, Lucena-Silva Norma, Donadi Eduardo A
Abstract excerpt
INTRODUCTION: Non-classical class I human leukocyte antigens (HLA) molecules are known to modulate the function of cytotoxic cells (NK and T CD8+) during viral infection by interacting with inhibitory/activating receptors. However, little is known about the HLA-E/-F genetic variability on arbovirus infections. METHODS: We evaluated by massive parallel sequencing the full HLA-E/-F genetic diversity among patients...
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