Congenital Zika Syndrome Is Associated With Interferon Alfa Receptor 1.

doi:10.3389/fimmu.2021.764746

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Article

Congenital Zika Syndrome Is Associated With Interferon Alfa Receptor 1.

Frontiers in immunology - 1 Jan 2021

Azamor Tamiris, Cunha Daniela Prado, da Silva Andréa Marques Vieira, Bezerra Ohanna Cavalcanti de Lima, Ribeiro-Alves Marcelo, Calvo Thyago Leal, Kehdy Fernanda de Souza Gomes, Manta Fernanda Saloum de Neves, Pinto Thiago Gomes de Toledo, Ferreira Laís Pereira, Portari Elyzabeth Avvad, Guida Letícia da Cunha, Gomes Leonardo, Moreira Maria Elisabeth Lopes, de Carvalho Elizeu Fagundes, Cardoso Cynthia Chester, Muller Marcelo, Ano Bom Ana Paula Dinis, Neves Patrícia Cristina da Costa, Vasconcelos Zilton, Moraes Milton Ozório

Abstract excerpt

Host factors that influence Congenital Zika Syndrome (CZS) outcome remain elusive. Interferons have been reported as the main antiviral factor in Zika and other flavivirus infections. Here, we accessed samples from 153 pregnant women (77 without and 76 with CZS) and 143 newborns (77 without and 66 with CZS) exposed to ZIKV conducted a case-control study to verify whether interferon alfa receptor 1 (IFNAR1) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34899713
DOI: 10.3389/fimmu.2021.764746
PMCID: PMC8657619

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