Article

Congenital Zika Syndrome is associated with interferon alfa receptor 1

2019-07-26

Abstract excerpt

<h4>Background</h4> Host factors that influence Congenital Zika Syndrome (CZS) outcome remain elusive. Interferons have been reported as the main antiviral factor in Zika and other flavivirus infections. <h4>Methods</h4> We accessed samples from Zika pregnancies, conducted a case-control study to verify whether interferon alfa receptor 1 ( IFNAR1 ) and interferon lambda 2 and 4 ( IFNL2/4 ) single nucleotide po...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c4e2b78c-621f-5d1e-86d8-1db14a44ddd3
DOI: 10.1101/715862

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Congenital Zika Syndrome is associated with interferon alfa receptor 1DOI 10.1101/715862Read

Congenital Zika Syndrome Is Associated With Interferon Alfa Receptor 1.Semantic proximity Read

Association between Maternal Non-Coding Interferon-λ Polymorphisms and Congenital Zika Syndrome in a Cohort from Brazilian Northeast.Semantic proximity Read

Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twinsSemantic proximity Read

Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins.Semantic proximity Read

Association between genetic variants in TREM1, CXCL10, IL4, CXCL8 and TLR7 genes with the occurrence of congenital Zika syndrome and severe microcephaly.Semantic proximity Read

Association Between Zika Virus Microcephaly in Newborns With the rs3775291 Variant in Toll-Like Receptor 3 and rs1799964 Variant at Tumor Necrosis Factor-α GeneSemantic proximity Read

Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent miceSemantic proximity Read

The HAVCR1-centric host factor network drives Zika virus vertical transmissionSemantic proximity Read

Zika Virus Pathogenesis: A Battle for Immune EvasionSemantic proximity Read

Biomarkers and immunoprofiles associated with fetal abnormalities of ZIKV-positive pregnanciesSemantic proximity Read

Downregulation of Transcriptional Activity, Increased Inflammation, and Damage in the Placenta Following in utero Zika Virus Infection Is Associated With Adverse Pregnancy OutcomesSemantic proximity Read

Hypothetical Human Immune Genome Complex Gradient May Help to Explain the Congenital Zika Symdrome Catastrophe in Brazil: A New TheorySemantic proximity Read