The cGAS/STING signaling pathway: a cross-talk of infection, senescence and tumors

Abstract excerpt

The cGAS/STING signaling pathway is an important part of the cytoplasmic DNA sensor, which can trigger a type I interferon response to microbial infection when pathogenic DNA is detected. However, continuous inhibition of cGAS/STING signaling by viral infection may be an important cause of tumorigenesis. At the same time, recent studies have shown that although the cGAS/STING signaling pathway also plays a core...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Inflammasome and immune disorders
• Share to interferon and immune responses
• Share to Viral Infections and Vectors