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Sex-specific association between coffee consumption and incident chronic kidney disease: a population-based analysis of 359,906 participants from the UK Biobank.

Chinese medical journal - 20 Jun 2022

Tang Lei, Yang Lina, Chen Wenwen, Li Chunyang, Zeng Yu, Yang Huazhen, Hu Yao, Qu Yuanyuan, Song Huan, Zeng Xiaoxi, Fu Ping

Abstract excerpt

BACKGROUND: The risk for chronic kidney disease (CKD) is influenced by genetic predisposition, sex, and lifestyle. Previous research indicates that coffee is a potentially protective factor in CKD. The current study aims to investigate whether sex disparity exists in the coffee-CKD association, and whether genetic risk of CKD or genetic polymorphisms of caffeine metabolism affect this association. METHODS: A...

Topics

Bayes Theorem
Biological Specimen Banks
Caffeine
Coffee
Female
Genetic Predisposition to Disease
Gonadal Steroid Hormones
Humans
Male
Prospective Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Renal Insufficiency, Chronic

Risk Factors

Sex Hormone-Binding Globulin

Testosterone

United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 35940879
DOI: 10.1097/CM9.0000000000002234
PMCID: PMC9481436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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