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Article

Impact of hyperuricemia on CKD risk beyond genetic predisposition in a population-based cohort study.

Scientific reports - 9 Aug 2024

Kim Yaerim, Jo Jinyeon, Ji Yunmi, Bae Eunjin, Lee Kwangbae, Paek Jin Hyuk, Jin Kyubok, Han Seungyeup, Lee Jung Pyo, Kim Dong Ki, Lim Chun Soo, Won Sungho, Lee Jeonghwan

Abstract excerpt

The bidirectional effect of hyperuricemia on chronic kidney disease (CKD) underscores the importance of hyperuricemia as a risk factor for CKD. We evaluated the effect of hyperuricemia on the presence and development of CKD after considering genetic background by calculating polygenic risk scores (PRSs). We employed genome-wide association study summary statistics-excluding the United Kingdom Biobank (UKB)...

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Identifiers

PMID: 39122851
DOI: 10.1038/s41598-024-69420-5
PMCID: PMC11316130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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