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Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study.

Nutrients - 18 Oct 2023

Giontella Alice, de La Harpe Roxane, Cronje Héléne T, Zagkos Loukas, Woolf Benjamin, Larsson Susanna C, Gill Dipender

Abstract excerpt

Caffeine is a psychoactive substance widely consumed worldwide, mainly via sources such as coffee and tea. The effects of caffeine on kidney function remain unclear. We leveraged the genetic variants in the CYP1A2 and AHR genes via the two-sample Mendelian randomization (MR) framework to estimate the association of genetically predicted plasma caffeine and caffeine intake on kidney traits. Genetic association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37892497
DOI: 10.3390/nu15204422
PMCID: PMC10609900

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