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Article

Prime editor-mediated correction of a pathogenic mutation in purebred dogs.

Scientific reports - 28 Jul 2022

Kim Dong Ern, Lee Ji Hye, Ji Kuk Bin, Lee Eun Ji, Li Chuang, Oh Hyun Ju, Park Kang Sun, Lee Seung Hoon, Koo Okjae, Kim Min Kyu

Abstract excerpt

Canine hip dysplasia (HD) is a multifactorial disease caused by interactions between genetic and environmental factors. HD, which mainly occurs in medium- to large-sized dogs, is a disease that causes severe pain and requires surgical intervention. However, the procedure is not straight-forward, and the only way to ameliorate the situation is to exclude individual dogs with HD from breeding programs. Recently,...

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Identifiers

PMID: 35902672
DOI: 10.1038/s41598-022-17200-4
PMCID: PMC9334597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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