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Prime Editor-mediated Correction of a Pathogenic Mutation in Purebred Dogs

2021-12-29

Abstract excerpt

Canine hip dysplasia (HD) is a multifactorial disease caused by interactions between genetic and environmental factors. HD, which mainly occurs in medium- to large-sized dogs, is a disease that causes severe pain and requires surgical intervention. However, the procedure is not straight-forward, and the only way to ameliorate the situation is to exclude individual dogs with HD from breeding programs. Recently, pri...

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Literature Corpus work
99281f39-3658-5b97-afd0-cd71a34e6355
DOI
10.21203/rs.3.rs-1105540/v1
Open publication

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Prime Editor-mediated Correction of a Pathogenic Mutation in Purebred DogsDOI 10.21203/rs.3.rs-1105540/v1
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