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Article

The correlation analysis of TERT promoter mutations with IDH1/2 mutations and 1p/19q detected in human gliomas.

Medicine - 22 Jul 2022

Xu Jie, Xu Fang-Ping, Liu Zhi-Hua, Cui Qian, Zhang Ke-Ping, Li Zhi

Abstract excerpt

BACKGROUND: To investigate the correlations between mutations in the telomerase reverse transcriptase (TERT) promoter and isocitrate dehydrogenase (IDH) 1 and 2 mutations or 1p/19q deletion in human gliomas. METHODS: TERT promoter gene and IDH gene mutations in 110 glioma specimens were evaluated using first generation Sanger sequencing. The 1p/19q status was determined with fluorescence in situ hybridization....

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Identifiers

PMID: 35866817
DOI: 10.1097/MD.0000000000029668
PMCID: PMC9302255

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