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Article

Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.

Journal of neuro-oncology - 1 May 2016

Ghasimi Soma, Wibom Carl, Dahlin Anna M, Brännström Thomas, Golovleva Irina, Andersson Ulrika, Melin Beatrice

Abstract excerpt

During the last years, genome wide association studies have discovered common germline genetic variants associated with specific glioma subtypes. We aimed to study the association between these germline risk variants and tumor phenotypes, including copy number aberrations and protein expression. A total of 91 glioma patients were included. Thirteen well known genetic risk variants in TERT, EGFR, CCDC26, CDKN2A,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26839018
DOI: 10.1007/s11060-016-2066-4
PMCID: PMC4835517

Genes

EGFR
RTEL1
IDH1
PHLDB1
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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