Article
The Y Chromosome: A Complex Locus for Genetic Analyses of Complex Human Traits.
Genes - 29 Oct 2020
Parker Katherine, Erzurumluoglu A Mesut, Rodriguez Santiago
Abstract excerpt
The Human Y chromosome (ChrY) has been demonstrated to be a powerful tool for phylogenetics, population genetics, genetic genealogy and forensics. However, the importance of ChrY genetic variation in relation to human complex traits is less clear. In this review, we summarise existing evidence about the inherent complexities of ChrY variation and their use in association studies of human complex traits. We...
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