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Article

Toehold-controlled ligation and transcription for accurate COVID-19 genotyping.

Analytical biochemistry - 1 Oct 2022

Gao Yanmin, Wang Taoxue, Li Jiaojiao, Wei Yanan, Qi Hao

Abstract excerpt

The global pandemic of coronavirus disease 2019 (COVID-19) has significant impact on the entire human society. However, in the face of continually emerging more contagious SARS-CoV-2 variant, the risk to bog down into more severe crisis is around us anytime. Here, we introduce an isothermal, ultrasensitive method for identifying important SNV mutations of SARS-CoV-2. It is based on combined specificity of...

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Identifiers

PMID: 35843299
DOI: 10.1016/j.ab.2022.114803
PMCID: PMC9283128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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