Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of a multiplexed oligonucleotide ligation assay for SARS-CoV-2 variant identification.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2023

Solis Daniel, Sibai Mamdouh, Kung Faith, Break Timothy J, Harkins Seth B, Huang ChunHong, Yamamoto Fumiko, Sahoo Malaya K, Wohlstadter Jacob N, Sigal George B, Pinsky Benjamin A

Abstract excerpt

BACKGROUND: SARS-CoV-2 variant surveillance informs vaccine composition and decisions to de-authorize antibody therapies. Though detailed genetic characterization requires whole-genome sequencing, targeted mutation analysis may complement pandemic surveillance efforts. METHODS: This study investigated the qualitative performance of a multiplex oligonucleotide ligation assay targeting 19 spike mutations using 192...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Assay
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Oligonucleotides

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 37043903
DOI: 10.1016/j.jcv.2023.105444
PMCID: PMC10076247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of a multiplexed oligonucleotide ligation assay for SARS-CoV-2 variant identification.PMID 37043903Read ↗

Ligation-Based Assay for Variant-Typing Without Sequencing: Application to SARS-CoV-2 Variants of ConcernSemantic proximity Read ↗

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping.Semantic proximity Read ↗

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotypingSemantic proximity Read ↗

Fluorometric Detection of SARS-CoV-2 Single-Nucleotide Variant L452R Using Ligation-Based Isothermal Gene AmplificationSemantic proximity Read ↗

Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome InsightsSemantic proximity Read ↗

Establishment of a Padlock Probe-Based Fluorescence Quantitative PCR Method for the Detection of the SARS-CoV-2 Omicron S371L Mutation.Semantic proximity Read ↗

DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencingSemantic proximity Read ↗

Targeted Amplification and Genetic Sequencing of the Severe Acute Respiratory Syndrome Coronavirus 2 Surface GlycoproteinSemantic proximity Read ↗

RPA-ligation-qPCR combined method for genotyping the SARS-CoV-2 key mutation E484Q.Semantic proximity Read ↗

Toehold-controlled ligation and transcription for accurate COVID-19 genotyping.Semantic proximity Read ↗

Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene.Semantic proximity Read ↗

Comparing library preparation methods for SARS-CoV-2 multiplex amplicon sequencing on the Illumina MiSeq platformSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.