Article

Ligation-Based Assay for Variant-Typing Without Sequencing: Application to SARS-CoV-2 Variants of Concern

2022-08-31

Abstract excerpt

Background: COVID-19 prevalence has remained high throughout the pandemic with intermittent surges, due largely to the emergence of genetic variants, demonstrating the need for more accessible sequencing technologies for strain typing.<br><br>Methods: A ligation-based typing assay was developed to detect know variants of SARS-CoV-2 by identifying the presence of characteristic single-nucleotide polymorphisms (SNPs...

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Literature Corpus work: ca146244-b07b-5606-82f0-aa5b298144bd
DOI: 10.2139/ssrn.4205779

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