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Development of a Real-Time qPCR Assay for Detection of Common MPL Mutations in Myeloproliferative Neoplasms (MPNS).

Applied biochemistry and biotechnology - 1 Dec 2022

Ullah Naeem, Khan Sadiq Noor, Umair Muhammad, Khan Aamir Ali, Liu Xinhui, Khattak Aamer Ali, Yousafzai Yasar Mehmood

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are blood cell disorders, characterized by overproduction of abnormal cells in bone marrow due to stem cell mutation. The proliferations of blood cell are controlled by many genes particularly MPL gene which encodes thrombopoietin receptor, a hematopoietic growth factor involved in the production and regulation of the platelets and multipotent hematopoietic progenitor cells....

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PMID: 35838887
DOI: 10.1007/s12010-022-04051-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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