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Mutations in myeloproliferative neoplasms - their significance and clinical use.

Expert review of hematology - 1 Nov 2017

Schischlik Fiorella, Kralovics Robert

Abstract excerpt

INTRODUCTION: Clonal hematologic diseases of the blood such as polycythemia vera, essential thrombocythemia and primary myelofibrosis belong to the BCR-ABL negative Myeloproliferative Neoplasms (MPN). These diseases are characterized by clonal expansion of hematopoietic precursor cells followed by increased production of differentiated cells of the myeloid lineage. Initiation of clonal hematopoiesis, formation of...

Topics

Humans
Mutation
Myeloproliferative Disorders
Prognosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28914569
DOI: 10.1080/17474086.2017.1380515

Genes

BCR

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