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Article

The Role of New Technologies in Myeloproliferative Neoplasms

26 Apr 2019

Abstract excerpt

The hallmark of BCR-ABL1-negative myeloproliferative neoplasms (MPNs) is the presence of a driver mutation in JAK2, CALR or MPL gene. These genetic alterations represent a key feature, useful for diagnostic, prognostic and therapeutical approaches. Molecular biology tests are now widely available with different specificity and sensitivity. Recently, the allele burden quantification of driver mutations has become...

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PMID: 31106152
DOI: 10.3389/fonc.2019.00321

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