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Article

Rapid real-time PCR assay for detection of MPL W515L mutation in patients with chronic myeloproliferative disorders.

International journal of laboratory hematology - 1 Feb 2010

Ghaderi M, Strömberg O, Porwit A

Abstract excerpt

Clinical diagnosis of the myeloproliferative disorders (MPD) has previously been based on clinical data and bone marrow morphology due to lack of specific molecular markers. The discovery of JAK2 V617F mutation has shed light on understanding of the molecular pathways involved in the pathogenesis of the myeloproliferative disorders. The thrombopoietin receptor gene (MPL) is expressed in megakaryocytes and...

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Source

Identifiers

PMID: 19016916
DOI: 10.1111/j.1751-553X.2008.01118.x

Genes

JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Rapid real-time PCR assay for detection of MPL W515L mutation in patients with chronic myeloproliferative disorders.PMID 19016916Read ↗

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