Article
Molecular diagnostics of myeloproliferative neoplasms.
European journal of haematology - 1 Oct 2015
Langabeer Stephen E, Andrikovics Hajnalka, Asp Julia, Bellosillo Beatriz, Carillo Serge, Haslam Karl, Kjaer Lasse, Lippert Eric, Mansier Olivier, Oppliger Leibundgut Elisabeth, Percy Melanie J, Porret Naomi, Palmqvist Lars, Schwarz Jiri, McMullin Mary F, Schnittger Susanne, Pallisgaard Niels, Hermouet Sylvie
Abstract excerpt
Since the discovery of the JAK2 V617F mutation in the majority of the myeloproliferative neoplasms (MPN) of polycythemia vera, essential thrombocythemia and primary myelofibrosis ten years ago, further MPN-specific mutational events, notably in JAK2 exon 12, MPL exon 10 and CALR exon 9 have been identified. These discoveries have been rapidly incorporated into evolving molecular diagnostic algorithms. Whilst many...
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