Article
Molecular landscape of IDH-wild type, pTERT-wild type adult glioblastomas.
Brain pathology (Zurich, Switzerland) - 1 Nov 2022
Liu Emma Munan, Shi Zhi-Feng, Li Kay Ka-Wai, Malta Tathiane M, Chung Nellie Yuk-Fei, Chen Hong, Chan Janice Yuen-Tung, Poon Manix Fung-Man, Kwan Johnny Sheung-Him, Chan Danny Tat-Ming, Noushmehr Houtan, Mao Ying, Ng Ho-Keung
Abstract excerpt
Telomerase reverse transcriptase (TERT) promoter (pTERT) mutation has often been described as a late event in gliomagenesis and it has been suggested as a prognostic biomarker in gliomas other than 1p19q codeleted tumors. However, the characteristics of isocitrate dehydrogenase (IDH) wild type (wt) (IDHwt), pTERTwt glioblastomas are not well known. We recruited 72 adult IDHwt, pTERTwt glioblastomas and performed...
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