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Article

Genetic LGALS1 Variants Are Associated with Heterogeneity in Galectin-1 Serum Levels in Patients with Early Arthritis.

International journal of molecular sciences - 28 Jun 2022

Triguero-Martínez Ana, Roy-Vallejo Emilia, Montes Nuria, de la Fuente Hortensia, Ortiz Ana María, Castañeda Santos, González-Álvaro Isidoro, Lamana Amalia

Abstract excerpt

Galectin 1 (Gal1) exerts immunomodulatory effects leading to therapeutic effects in autoimmune animal models. Patients with rheumatoid arthritis have been reported to show higher Gal1 serum levels than the healthy population. Our study aimed to find genetic variants on the Gal1 gene (LGALS1) modulating its expression and/or clinical features in patients with early arthritis (EA). LGALS1 was sequenced in 53 EA...

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Identifiers

PMID: 35806182
DOI: 10.3390/ijms23137181
PMCID: PMC9266574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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