Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PharmVar GeneFocus: SLCO1B1.

Clinical pharmacology and therapeutics - 1 Apr 2023

Ramsey Laura B, Gong Li, Lee Seung-Been, Wagner Jonathan B, Zhou Xujia, Sangkuhl Katrin, Adams Solomon M, Straka Robert J, Empey Philip E, Boone Erin C, Klein Teri E, Niemi Mikko, Gaedigk Andrea

Abstract excerpt

The Pharmacogene Variation Consortium (PharmVar) is now providing star (*) allele nomenclature for the highly polymorphic human SLCO1B1 gene encoding the organic anion transporting polypeptide 1B1 (OATP1B1) drug transporter. Genetic variation within the SLCO1B1 gene locus impacts drug transport, which can lead to altered pharmacokinetic profiles of several commonly prescribed drugs. Variable OATP1B1 function is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cytochrome P-450 Enzyme System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Transport and Resistance Mechanisms

Share to Genetic Associations and Epidemiology

Share to Haplotypes

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Liver-Specific Organic Anion Transporter 1

Share to Pharmacogenetics

Source

Open in PubMed Open full text

Identifiers

PMID: 35797228
DOI: 10.1002/cpt.2705
PMCID: PMC10900141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PharmVar GeneFocus: SLCO1B1.PMID 35797228Read ↗

PharmVar GeneFocus: CYP1A2-Clinical Impact, Genetic Variation, and Updated Nomenclature.Semantic proximity Read ↗

PharmVar GeneFocus: CYP3A5.Semantic proximity Read ↗

PharmVar GeneFocus: CYP4F2.Semantic proximity Read ↗

PharmGKB very important pharmacogene: SLCO1B1.Semantic proximity Read ↗

PharmVar GeneFocus: CYP2C9.Semantic proximity Read ↗

PharmVar GeneFocus: CYP2C19.Semantic proximity Read ↗

Genetic variability and population diversity of the human SLCO (OATP) transporter familySemantic proximity Read ↗

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.Semantic proximity Read ↗

Large-scale next generation sequencing based analysis of SLCO1B1 pharmacogenetics variants in the Saudi population.Semantic proximity Read ↗

SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients.Semantic proximity Read ↗

A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance.Semantic proximity Read ↗

SLCO1B1 Functional Variants, Bilirubin, Statin-Induced Myotoxicity, and Recent Sub-Saharan African Ancestry: A Precision Medicine Health Equity Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.