Article
[miR-151-3p derived from gastric cancer exosomes induces M2-phenotype polarization of macrophages and promotes tumor growth].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Jul 2022
Xie Shilin, Zhu Yuekun, Wang Shuo, Yang Xiuding, Yuan Xiaowei, Piao Daxun
Abstract excerpt
Objective To investigate whether exosomes derived from gastric cancer cells can affect macrophages in tumor microenvironment through miR-151-3p. Methods The expression of miR-151-3p in tumor tissues of patients with gastric cancer and normal tissues was detected by real time quantitative PCR; Gastric cancer cells overexpressing miR-151-3p were constructed, and exosomes were isolated and identified. The expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
