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Gastric cancer cell-derived exosomal miR-541-5p induces M2 macrophage polarization through DUSP3/JAK2/STAT3 pathway

6 Aug 2024

Abstract excerpt

PURPOSE: Exosomal microRNAs have been identified as important mediators of communication between tumor cells and macrophages in the microenvironment. miR-541-5p was reported to be involved in hepatocellular carcinoma progression, but its role in gastric cancer (GC) and in GC cell-macrophage crosstalk is unknown. METHODS: cell population was analyzed by flow cytometry. Western blotting was employed to evaluate...

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PMID: 39103776
DOI: 10.1186/s12885-024-12672-1

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