Article
Unique prediction of developmental psychopathology from genetic and familial risk.
Journal of child psychology and psychiatry, and allied disciplines - 1 Dec 2022
Loughnan Robert J, Palmer Clare E, Makowski Carolina, Thompson Wesley K, Barch Deanna M, Jernigan Terry L, Dale Anders M, Fan Chun Chieh
Abstract excerpt
BACKGROUND: Early detection is critical for easing the rising burden of psychiatric disorders. However, the specificity of psychopathological measurements and genetic predictors is unclear among youth. METHODS: We measured associations between genetic risk for psychopathology (polygenic risk scores (PRS) and family history (FH) measures) and a wide range of behavioral measures in a large sample (n = 5,204) of...
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