Exploring the Behavioral and Emotional Manifestation of Polygenic Risk for Psychiatric Disorders Among Schoolchildren.

doi:10.1016/j.jaac.2025.06.012

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Article

Exploring the Behavioral and Emotional Manifestation of Polygenic Risk for Psychiatric Disorders Among Schoolchildren.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Apr 2026

Alemany Silvia, Bosch Rosa, Soler Artigas María, Cabana-Domínguez Judit, Vilar-Ribó Laura, Llonga Natalia, Arribas Lorena, Carabí-Gassol Pau, Macias-Chimborazo Valeria, Zubizarreta-Arruti Uxue, Pagerols Mireia, Prat Raquel, Pagespetit Èlia, Puigbó Julia, Español-Martín Gemma, Ramos-Quiroga J Antoni, Casas Miquel, Ribasés Marta

Abstract excerpt

OBJECTIVE: We examined the relationships between polygenic risk scores (PRS) for psychiatric disorders and behavioral and emotional problems. In addition, we explored whether these associations differed by sex and conducted mutually adjusted models to elucidate whether different PRS independently contributed to the same outcome. METHOD: Participants included 4,709 individuals 5 to 18 years of age from the Spanish...

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PMID: 40543799
DOI: 10.1016/j.jaac.2025.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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