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Article

Using Genetics to Examine a General Liability to Childhood Psychopathology.

Behavior genetics - 1 Jul 2020

Riglin Lucy, Thapar Ajay K, Leppert Beate, Martin Joanna, Richards Alexander, Anney Richard, Davey Smith George, Tilling Kate, Stergiakouli Evie, Lahey Benjamin B, O'Donovan Michael C, Collishaw Stephan, Thapar Anita

Abstract excerpt

Psychiatric disorders show phenotypic as well as genetic overlaps. There are however also marked developmental changes throughout childhood. We investigated the extent to which, for a full range of early childhood psychopathology, a general "p" factor was explained by genetic liability, as indexed by multiple different psychiatric polygenic risk scores (PRS) and whether these relationships altered with age. The...

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Identifiers

PMID: 31828458
DOI: 10.1007/s10519-019-09985-4
PMCID: PMC7355267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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