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Article

Dissecting the clinical relevance of polygenic risk score for obesity-a cross-sectional, longitudinal analysis.

International journal of obesity (2005) - 1 Sept 2022

Choe Eun Kyung, Shivakumar Manu, Lee Seung Mi, Verma Anurag, Kim Dokyoon

Abstract excerpt

BACKGROUND: Obesity is a global pandemic disease whose prevalence is increasing worldwide. The clinical relevance of a polygenic risk score (PRS) for obesity has not been fully elucidated in Asian populations. METHOD: We utilized a comprehensive health check-up database from the Korean population in conjunction with genotyping to generate PRS for BMI (PRS-BMI). We conducted a phenome-wide association (PheWAS)...

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Identifiers

PMID: 35752651
DOI: 10.1038/s41366-022-01168-2
PMCID: PMC10362905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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