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Article

Development of a Polygenic Risk Score for BMI to Assess the Genetic Susceptibility to Obesity and Related Diseases in the Korean Population.

International journal of molecular sciences - 17 Jul 2023

Yoon Nara, Cho Yoon Shin

Abstract excerpt

Hundreds of genetic variants for body mass index (BMI) have been identified from numerous genome-wide association studies (GWAS) in different ethnicities. In this study, we aimed to develop a polygenic risk score (PRS) for BMI for predicting susceptibility to obesity and related traits in the Korean population. For this purpose, we obtained base data resulting from a GWAS on BMI using 57,110 HEXA study subjects...

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Identifiers

PMID: 37511320
DOI: 10.3390/ijms241411560
PMCID: PMC10380444

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