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Article

Genetic determinants of obesity in Korean populations: exploring genome-wide associations and polygenic risk scores.

Briefings in bioinformatics - 25 Jul 2024

Jo Jinyeon, Ha Nayoung, Ji Yunmi, Do Ahra, Seo Je Hyun, Oh Bumjo, Choi Sungkyoung, Choe Eun Kyung, Lee Woojoo, Son Jang Won, Won Sungho

Abstract excerpt

East Asian populations exhibit a genetic predisposition to obesity, yet comprehensive research on these traits is limited. We conducted a genome-wide association study (GWAS) with 93,673 Korean subjects to uncover novel genetic loci linked to obesity, examining metrics such as body mass index, waist circumference, body fat ratio, and abdominal fat ratio. Participants were categorized into non-obese, metabolically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39207728
DOI: 10.1093/bib/bbae389
PMCID: PMC11359806

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