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Article

Plasma levels of efavirenz and frequency of the CYP2B6 516G>T polymorphism in people living with HIV-1 in Mexico.

Die Pharmazie - 1 Jun 2022

Ortíz-Rodríguez M A, Oaxaca-Navarro J, Patiño-Camacho S I, García-Jiménez S, Déciga-Campos M, Martínez-Salazar M F

Abstract excerpt

Efavirenz (EFV) is a widely used antiretroviral, due to its safety, efficacy, and low cost. However, plasma concentrations have been related with an increased risk of virological failure and the appearance of serious adverse reactions. EFV is metabolized by Cytochrome P450, the main isoenzyme involved is CYP2B6 and the most relevant genetic polymorphisms found in several populations has been the CYP2B6 516G> T....

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Identifiers

PMID: 35751161
DOI: 10.1691/ph.2022.2382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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