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matOptimize: a parallel tree optimization method enables online phylogenetics for SARS-CoV-2

22 Jun 2022

Abstract excerpt

MOTIVATION: Phylogenetic tree optimization is necessary for precise analysis of evolutionary and transmission dynamics, but existing tools are inadequate for handling the scale and pace of data produced during the coronavirus disease 2019 (COVID-19) pandemic. One transformative approach, online phylogenetics, aims to incrementally add samples to an ever-growing phylogeny, but there are no previously existing...

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PMID: 35731204
DOI: 10.1093/bioinformatics/btac401

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